MRPS18CP6

Across TCGA pan-cancer cohorts, MRPS18CP6 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MRPS18CP6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MRPS18CP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPS18CP6 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

KIRP, COAD, and BRCA are the cancer types where MRPS18CP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS18CP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	+0.228	.001	6	view →
COAD	All	II,III,IV	+0.164	.009	5	view →
BRCA	All	II,III,IV	−0.173	.002	4	view →
THCA	Male	IV	−0.316	<.001	3	view →
KIRC	All	IV	+0.178	.006	3	view →
CHOL	All	All	+0.437	.002	2	view →
KICH	Female	II,III,IV	−0.392	.005	2	view →
BLCA	Female	III,IV	−0.272	.021	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MRPS18CP6–KIRP

Open the KIRP breakdown →