MRPS18C

Across TCGA patient cohorts, MRPS18C mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible MRPS18C-associated genes across cancer lineages are USP9YP2, RNU6-837P, and OR10J6P. Each is linked with MRPS18C in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS18C-to-partner and partner-to-MRPS18C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by MRPS18C-low versus MRPS18C-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18C→partner) and Y-score (partner→MRPS18C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	USP9YP2 →	+0.039	+7.640	<.001	.009	3	2
THCA	RNU6-837P →	+0.978	+7.962	<.001	.007	3	1
UCEC	OR10J6P →	+0.129	+4.621	<.001	.008	3	1
BRCA	RNU6-845P →	+0.489	+9.057	<.001	.003	3	1
BRCA	RNU7-27P →	+0.422	+8.055	<.001	.007	3	1
BLCA	MIR5591 →	+0.420	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

USP9YP2 by MRPS18C expression — BLCA

Explore this box plot interactively →