Across TCGA pan-cancer cohorts, MRPS18BP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MRPS18BP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPS18BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPS18BP1 is over-expressed in tumor.
KIRC are the cancer types where MRPS18BP1 tumor–normal differential expression is most reproducible.