Across TCGA patient cohorts, MRPS18B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS18B-associated genes across cancer lineages are eEF2, A-Raf_pS299, and INPP4B. Each is linked with MRPS18B in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS18B-to-partner and partner-to-MRPS18B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18B→partner) and Y-score (partner→MRPS18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.507	+3.169	.004	.019	3	1
UCEC	A-Raf_pS299 →	-0.183	-2.321	.002	.035	3	1
UCEC	INPP4B →	-0.385	-2.999	.017	.035	3	1
UCEC	MEK1 →	+0.381	+2.321	.038	.035	3	1
UCEC	p62 Lck ligand →	+0.466	+3.009	.004	.019	3	1
UCEC	Paxillin →	+0.305	+2.820	.019	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

MRPS18B survival (RNA) · tumor vs normal (RNA) · all MRPS18B data types