MRPS18A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRPS18A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS18A-associated genes across cancer lineages are lymphatic Endothelial cells, Endothelial cells, and Plasma cells. Each is linked with MRPS18A in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS18A-to-partner and partner-to-MRPS18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by MRPS18A-low versus MRPS18A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18A→partner) and Y-score (partner→MRPS18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEClymphatic Endothelial cells →-0.027-2.946.045.03721
UCECEndothelial cells →-0.044-2.957.048.03711
UCECPlasma cells →-0.025-2.957.042.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

lymphatic Endothelial cells by MRPS18A expression — UCEC

Box plot of lymphatic Endothelial cells in MRPS18A-low vs MRPS18A-high samples in UCEC.

Explore this box plot interactively →

Exploration