MRPS18A

Across TCGA cell cohorts, MRPS18A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,360 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPS18A-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, rRNA methylation, and Ketone biosynthetic process. Each is linked with MRPS18A in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPS18A-to-partner and partner-to-MRPS18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by MRPS18A-low versus MRPS18A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18A→partner) and Y-score (partner→MRPS18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.126	+0.757	<.001	.002	1	14
LUNG_SCLC	rRNA methylation →	+0.078	+0.437	<.001	<.001	3	8
LARGE_INTESTINE	Ketone biosynthetic process →	+0.082	+0.353	<.001	<.001	3	8
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.099	+0.836	.005	.004	2	8
LUNG_NSCLC_LUAD	Regulation of pigment cell differentiation →	+0.155	+0.555	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Positive regulation of pigment cell differentiation →	+0.155	+0.555	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,360 associations by consensus.

Protein peptidyl-prolyl isomerization by MRPS18A expression — PANCREAS

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