MRPS17

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRPS17 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS17-associated genes across cancer lineages are Erythrocytes and pDC. Each is linked with MRPS17 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS17-to-partner and partner-to-MRPS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by MRPS17-low versus MRPS17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS17→partner) and Y-score (partner→MRPS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECErythrocytes →+0.039+3.169.004.02031
UCECpDC →+0.105+3.180<.001.01021
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Erythrocytes by MRPS17 expression — UCEC

Box plot of Erythrocytes in MRPS17-low vs MRPS17-high samples in UCEC.

Explore this box plot interactively →

Exploration