MRPS17

Across TCGA cell cohorts, MRPS17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,045 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPS17-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Mitochondrial gene expression, and tRNA metabolic process. Each is linked with MRPS17 in more than 11 cancer types. Because this analysis shows association rather than direction, both MRPS17-to-partner and partner-to-MRPS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by MRPS17-low versus MRPS17-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS17→partner) and Y-score (partner→MRPS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maturation of SSU-rRNA →	+0.127	+0.925	<.001	<.001	3	12
BONE	Mitochondrial gene expression →	+0.116	+0.804	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	tRNA metabolic process →	+0.068	+0.924	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Ribosome biogenesis →	+0.100	+0.926	<.001	.001	3	10
BONE	Regulation of mitochondrial translation →	+0.084	+0.751	<.001	<.001	3	10
BONE	Pseudouridine synthesis →	+0.105	+0.778	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,045 associations by consensus.

Maturation of SSU-rRNA by MRPS17 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →