MRPS17

Across TCGA cell cohorts, MRPS17 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPS17-associated genes across cancer lineages are MAGEB4, TDO2, and TUBA3E. Each is linked with MRPS17 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS17-to-partner and partner-to-MRPS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by MRPS17-low versus MRPS17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS17→partner) and Y-score (partner→MRPS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	TDO2 →	+2.113	+3.064	<.001	.009	3	1
LARGE_INTESTINE	TUBA3E →	+0.105	+3.369	<.001	.007	3	1
LARGE_INTESTINE	CX3CR1 →	+0.146	+3.215	<.001	.009	3	1
LARGE_INTESTINE	FAM153B →	+0.456	+2.841	<.001	.004	3	1
LARGE_INTESTINE	TAFA1 →	+0.187	+3.009	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MAGEB4 by MRPS17 expression — LARGE_INTESTINE

Explore this box plot interactively →