MRPS16P2

Across TCGA pan-cancer cohorts, MRPS16P2 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MRPS16P2 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MRPS16P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPS16P2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

CESC, UCEC, and KIRP are the cancer types where MRPS16P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
UCEC	DFS	Tertile	II,III,IV	0.597	0.757	.030	36	view →
KIRP	DFS	Tertile	IV	0.088	0.502	<.001	36	view →
BLCA	DFS	Tertile	III,IV	0.800	0.425	.029	21	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	21	view →
LGG	OS	Tertile	All	0.320	0.454	.004	18	view →
STAD	DFS	Tertile	IV	0.670	0.171	.013	15	view →
ESCA	DFS	Quartile	IV	0.826	0.288	.049	12	view →
OV	OS	Tertile	All	0.783	0.856	.030	12	view →
COAD	DFS	Tertile	All	0.632	0.807	.006	12	view →
LIHC	OS	Tertile	II,III,IV	0.905	0.692	.039	3	view →
SARC	OS	Tertile	All	0.630	0.830	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MRPS16P2–CESC (OS)

Open the CESC breakdown →