MRPS16

Across TCGA cell cohorts, MRPS16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,103 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPS16-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Mitochondrial DNA replication, and Regulation of mitochondrial RNA catabolic process. Each is linked with MRPS16 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPS16-to-partner and partner-to-MRPS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by MRPS16-low versus MRPS16-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS16→partner) and Y-score (partner→MRPS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.149	+0.921	<.001	<.001	3	13
URINARY_TRACT	Mitochondrial DNA replication →	+0.172	+0.925	<.001	<.001	3	12
URINARY_TRACT	Regulation of mitochondrial RNA catabolic process →	+0.143	+0.681	.001	.008	3	12
LUNG_NSCLC_LUSC	DNA replication, removal of RNA primer →	+0.136	+0.837	<.001	<.001	3	12
URINARY_TRACT	Mitochondrial DNA metabolic process →	+0.100	+0.733	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of mitochondrial RNA catabolic process →	+0.128	+0.662	.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,103 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by MRPS16 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →