MRPS11

Across TCGA cell cohorts, MRPS11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,830 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MRPS11-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Mitotic DNA replication checkpoint signaling, and DNA replication-dependent chromatin assembly. Each is linked with MRPS11 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPS11-to-partner and partner-to-MRPS11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle checkpoint grouped by MRPS11-low versus MRPS11-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS11→partner) and Y-score (partner→MRPS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of cell cycle checkpoint →	+0.082	+0.694	<.001	<.001	3	13
PANCREAS	Mitotic DNA replication checkpoint signaling →	+0.154	+0.702	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.152	+1.104	<.001	<.001	3	12
PANCREAS	DNA replication checkpoint signaling →	+0.171	+0.710	<.001	<.001	3	12
BLOOD_Lymphoma	Succinate transport →	+0.131	+0.385	<.001	.006	3	11
PANCREAS	Positive regulation of mitotic sister chromatid separation →	+0.135	+0.626	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,830 associations by consensus.

Regulation of cell cycle checkpoint by MRPS11 expression — OVARY

Explore this box plot interactively →