Across TCGA pan-cancer cohorts, MRPS10P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MRPS10P1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where MRPS10P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPS10P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
LUAD and KIRC are the cancer types where MRPS10P1 tumor–normal differential expression is most reproducible.