MRPL9

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MRPL9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,341 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible MRPL9-associated GO terms across cancer lineages are Nuclear division, Spindle elongation, and DNA replication checkpoint signaling. Each is linked with MRPL9 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPL9-to-partner and partner-to-MRPL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by MRPL9-low versus MRPL9-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL9→partner) and Y-score (partner→MRPL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCNuclear division →+0.060+0.630<.001<.001313
PANCREASSpindle elongation →+0.221+0.470<.001<.001313
SOFT_TISSUEDNA replication checkpoint signaling →+0.132+0.503<.001<.001313
UPPER_AERODIGESTIVE_TRACTRegulation of DNA-templated DNA replication →+0.143+0.783<.001<.001313
BONEDouble-strand break repair via break-induced replication →+0.230+0.876.009.001313
UPPER_AERODIGESTIVE_TRACTRegulation of metaphase/anaphase transition of cell cycle →+0.103+0.627.002<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

Nuclear division by MRPL9 expression — LUNG_SCLC

Box plot of Nuclear division in MRPL9-low vs MRPL9-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration