MRPL58

Across TCGA patient cohorts, MRPL58 protein abundance is significantly associated with the RNA expression of many other genes, with 15,183 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL58-associated genes across cancer lineages are MT-CO2, FYN, and PPFIA2. Each is linked with MRPL58 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPL58-to-partner and partner-to-MRPL58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL58 versus MT-CO2 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL58→partner) and Y-score (partner→MRPL58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT-CO2 →	+0.939	+0.216	<.001	<.001	3	8
UCEC	FYN →	-0.906	-0.287	.001	.003	3	7
PDAC	PPFIA2 →	-0.777	-0.331	<.001	<.001	3	7
BRCA	LRRC4C →	-1.067	-0.281	<.001	<.001	3	7
BRCA	COLEC12 →	-1.175	-0.396	<.001	<.001	3	7
UCEC	STARD9 →	-0.792	-0.383	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,183 associations by consensus.

MRPL58 vs MT-CO2 — HNSC

Explore this scatter interactively →