MRPL57P7

Across TCGA pan-cancer cohorts, MRPL57P7 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MRPL57P7 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MRPL57P7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL57P7 expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

KIRC, STAD, and PAAD are the cancer types where MRPL57P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.448	0.651	<.001	174	view →
STAD	OS	Tertile	All	0.766	0.614	.007	53	view →
PAAD	OS	Tertile	II,III,IV	0.223	0.588	.006	45	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	30	view →
OV	DFS	Tertile	IV	0.166	0.480	.006	30	view →
HNSC	OS	Tertile	All	0.828	0.645	.007	30	view →
ESCA	OS	Quartile	III,IV	0.792	0.349	.009	18	view →
LUAD	OS	Tertile	III,IV	0.223	0.677	.006	18	view →
ACC	OS	Tertile	All	0.118	0.624	.038	18	view →
COAD	DFS	Tertile	All	0.112	0.563	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MRPL57P7–KIRC (OS)

Open the KIRC breakdown →