MRPL57P1

Across TCGA patient cohorts, MRPL57P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 2,712 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MRPL57P1-associated proteins across cancer lineages are WRAP53_S491, MAP1B_T1949, and ADD2_S613. Each is linked with MRPL57P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL57P1-to-partner and partner-to-MRPL57P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL57P1 versus WRAP53_S491 in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL57P1→partner) and Y-score (partner→MRPL57P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WRAP53_S491 →	-0.412	-0.742	.003	<.001	3	2
LSCC	MAP1B_T1949 →	+1.116	+0.098	.003	.007	3	2
LSCC	ADD2_S613 →	+1.160	+0.131	.008	.008	3	2
LSCC	NAF1_S315 →	-0.326	-0.092	.003	.007	3	2
PDAC	WTAP_S306 →	-0.355	-0.067	.001	.008	3	2
PDAC	ASAP1_S816 →	+0.590	+0.110	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,712 associations by consensus.

MRPL57P1 vs WRAP53_S491 — GBM

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