MRPL57

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRPL57 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL57-associated proteins across cancer lineages are ZMYM2, MIPEP, and PDS5B. Each is linked with MRPL57 in more than 4 cancer types. Because this analysis shows association rather than direction, both MRPL57-to-partner and partner-to-MRPL57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL57 versus ZMYM2 in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL57→partner) and Y-score (partner→MRPL57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCZMYM2 →+0.365+0.430<.001<.00135
OVMIPEP →+0.498+0.506<.001.00335
LSCCPDS5B →+0.324+0.496<.001<.00135
GBMGTF2F2 →+0.445+0.287<.001<.00135
GBMRAC2 →-0.534-0.248<.001<.00134
LSCCZNF142_S904 →+0.431+0.434.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,848 associations by consensus.

MRPL57 vs ZMYM2 — LSCC

Per-sample scatter of MRPL57 vs ZMYM2 in LSCC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration