MRPL57

Across TCGA cell cohorts, MRPL57 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,060 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRPL57-associated GO terms across cancer lineages are Negative regulation of neuron apoptotic process, Wound healing, and Extracellular matrix organization. Each is linked with MRPL57 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPL57-to-partner and partner-to-MRPL57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of neuron apoptotic process grouped by MRPL57-low versus MRPL57-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL57→partner) and Y-score (partner→MRPL57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of neuron apoptotic process →	-0.100	-0.833	<.001	<.001	3	13
BONE	Wound healing →	-0.128	-0.924	<.001	<.001	3	11
BONE	Extracellular matrix organization →	-0.182	-0.796	<.001	<.001	3	11
BONE	Extracellular structure organization →	-0.181	-0.796	<.001	<.001	3	11
BONE	External encapsulating structure organization →	-0.181	-0.654	<.001	<.001	3	11
OESOPHAGUS	Coagulation →	-0.103	-0.809	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,060 associations by consensus.

Negative regulation of neuron apoptotic process by MRPL57 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →