MRPL54

Across TCGA patient cohorts, MRPL54 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MRPL54-associated genes across cancer lineages are MPP, Preadipocytes, and HSC. Each is linked with MRPL54 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL54-to-partner and partner-to-MRPL54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by MRPL54-low versus MRPL54-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL54→partner) and Y-score (partner→MRPL54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPP →	+0.022	+1.782	.001	.045	3	2
COAD	Preadipocytes →	+0.092	+4.169	<.001	.027	3	1
SKCM	HSC →	-0.095	-2.290	.020	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MPP by MRPL54 expression — SKCM

Explore this box plot interactively →