MRPL54

Across TCGA cell cohorts, MRPL54 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,395 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPL54-associated GO terms across cancer lineages are Regulation of neurogenesis, Cerebral cortex radial glia-guided migration, and Telencephalon glial cell migration. Each is linked with MRPL54 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL54-to-partner and partner-to-MRPL54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of neurogenesis grouped by MRPL54-low versus MRPL54-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL54→partner) and Y-score (partner→MRPL54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of neurogenesis →	-0.044	-0.617	<.001	.002	3	14
BONE	Cerebral cortex radial glia-guided migration →	-0.166	-0.722	.001	.002	3	13
BONE	Telencephalon glial cell migration →	-0.166	-0.722	.001	.002	3	13
BONE	Positive regulation of neurogenesis →	-0.052	-0.774	.008	<.001	3	13
BREAST	[2Fe-2S] cluster assembly →	+0.131	+0.829	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Glial cell migration →	-0.135	-0.568	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,395 associations by consensus.

Regulation of neurogenesis by MRPL54 expression — PANCREAS

Explore this box plot interactively →