MRPL52

Across TCGA cell cohorts, MRPL52 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,624 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MRPL52-associated GO terms across cancer lineages are Protein linear polyubiquitination, Nuclear histone mRNA catabolic process, and [4Fe-4S] cluster assembly. Each is linked with MRPL52 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL52-to-partner and partner-to-MRPL52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by MRPL52-low versus MRPL52-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL52→partner) and Y-score (partner→MRPL52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Protein linear polyubiquitination →	+0.142	+0.716	<.001	<.001	3	14
KIDNEY	Nuclear histone mRNA catabolic process →	+0.128	+0.806	.002	.003	3	12
UPPER_AERODIGESTIVE_TRACT	[4Fe-4S] cluster assembly →	+0.179	+1.194	<.001	<.001	3	10
SKIN	Positive regulation of protein localization to chromatin →	+0.108	+0.582	<.001	<.001	3	10
PANCREAS	Response to manganese-induced endoplasmic reticulum stress →	+0.076	+0.636	.001	.003	3	9
KIDNEY	Pericentric heterochromatin formation →	+0.129	+0.637	.006	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,624 associations by consensus.

Protein linear polyubiquitination by MRPL52 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →