MRPL48P1

Across TCGA patient cohorts, MRPL48P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,629 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRPL48P1-associated GO terms across cancer lineages are DNA conformation change, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and DNA integrity checkpoint signaling. Each is linked with MRPL48P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MRPL48P1-to-partner and partner-to-MRPL48P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA conformation change grouped by MRPL48P1-low versus MRPL48P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL48P1→partner) and Y-score (partner→MRPL48P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA conformation change →	+0.040	+0.089	<.001	<.001	3	13
STAD	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.045	+0.081	<.001	<.001	3	12
STAD	DNA integrity checkpoint signaling →	+0.043	+0.093	<.001	<.001	3	11
STAD	Methylation →	+0.036	+0.084	<.001	<.001	3	11
STAD	Ribosome assembly →	+0.043	+0.090	<.001	<.001	3	11
STAD	Amino acid activation →	+0.060	+0.162	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,629 associations by consensus.

DNA conformation change by MRPL48P1 expression — STAD

Explore this box plot interactively →