MRPL48

Across TCGA patient cohorts, MRPL48 protein abundance is significantly associated with the RNA expression of many other genes, with 13,363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL48-associated genes across cancer lineages are MT-CO2, VSTM4, and ZEB2. Each is linked with MRPL48 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL48-to-partner and partner-to-MRPL48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL48 versus MT-CO2 in HNSC, with a Pearson correlation of 0.21.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL48→partner) and Y-score (partner→MRPL48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT-CO2 →	+0.779	+0.160	.004	.003	2	7
LUAD	VSTM4 →	-0.770	-0.308	<.001	<.001	3	6
BRCA	ZEB2 →	-0.810	-0.336	<.001	<.001	3	6
BRCA	DACT3 →	-0.742	-0.321	<.001	.001	3	6
BRCA	MAGI2-AS3 →	-0.754	-0.288	<.001	<.001	3	6
LSCC	EDNRA →	-1.052	-0.325	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,363 associations by consensus.

MRPL48 vs MT-CO2 — HNSC

Explore this scatter interactively →