MRPL48

Across TCGA cell cohorts, MRPL48 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,297 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL48-associated GO terms across cancer lineages are Asparaginyl-tRNA aminoacylation, Negative regulation of immune effector process, and Carbohydrate derivative catabolic process. Each is linked with MRPL48 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRPL48-to-partner and partner-to-MRPL48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Asparaginyl-tRNA aminoacylation grouped by MRPL48-low versus MRPL48-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL48→partner) and Y-score (partner→MRPL48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Asparaginyl-tRNA aminoacylation →	+0.206	+0.874	<.001	<.001	3	16
LIVER	Negative regulation of immune effector process →	-0.171	-0.956	<.001	.007	3	10
CNS	Carbohydrate derivative catabolic process →	-0.059	-0.476	.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of leukocyte mediated immunity →	-0.116	-1.182	.006	.005	3	10
KIDNEY	DAMP biosynthetic process →	+0.104	+0.499	.002	.001	3	10
KIDNEY	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.104	+0.499	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,297 associations by consensus.

Asparaginyl-tRNA aminoacylation by MRPL48 expression — STOMACH

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