MRPL47

Across TCGA pan-cancer cohorts, MRPL47 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MRPL47 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MRPL47 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPL47 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, CCRCC, and LUAD are the cancer types where MRPL47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	II,III,IV	0.504	0.256	.012	11	view →
CCRCC	OS	Median	IV	0.123	0.785	.009	9	view →
LUAD	DFS	Median	All	0.545	0.880	.028	7	view →
LSCC	OS	Median	All	1.000	0.924	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MRPL47–PDAC (DFS)

Open the PDAC breakdown →