MRPL47

Across TCGA patient cohorts, MRPL47 mutation is significantly associated with the RNA expression of many other genes, with 362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL47-associated genes across cancer lineages are RNA5SP136, PCNPP2, and RNU6-373P. Each is linked with MRPL47 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL47-to-partner and partner-to-MRPL47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP136 grouped by MRPL47-low versus MRPL47-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL47→partner) and Y-score (partner→MRPL47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP136 →	+0.274	+2.599	<.001	.006	3	2
UCEC	PCNPP2 →	+0.041	+3.003	<.001	.007	3	2
COAD	RNU6-373P →	+1.908	+5.693	<.001	.003	3	2
COAD	MIR3140 →	+2.095	+5.602	<.001	.004	3	2
COAD	OR56B2P →	+0.110	+6.392	<.001	.001	3	1
HNSC	MIR3683 →	+0.338	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

RNA5SP136 by MRPL47 expression — UCEC

Explore this box plot interactively →