MRPL47

Across TCGA cell cohorts, MRPL47 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,528 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MRPL47-associated GO terms across cancer lineages are Regulation of cardiolipin metabolic process, Mitochondrial translational elongation, and Mitochondrial gene expression. Each is linked with MRPL47 in more than 14 cancer types. Because this analysis shows association rather than direction, both MRPL47-to-partner and partner-to-MRPL47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiolipin metabolic process grouped by MRPL47-low versus MRPL47-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL47→partner) and Y-score (partner→MRPL47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of cardiolipin metabolic process →	+0.177	+0.916	<.001	<.001	3	15
BONE	Mitochondrial translational elongation →	+0.105	+0.646	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitochondrial gene expression →	+0.099	+1.051	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, centromeric region →	+0.113	+0.935	.005	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translation →	+0.106	+1.081	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Lipid translocation →	-0.108	-0.984	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,528 associations by consensus.

Regulation of cardiolipin metabolic process by MRPL47 expression — BREAST

Explore this box plot interactively →