Across TCGA pan-cancer cohorts, MRPL45P2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MRPL45P2 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MRPL45P2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL45P2 expression acts as an unfavorable survival marker.

CESC and OV are the cancer types where MRPL45P2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.203	0.798	.001	18	view →
OV	DFS	Median	All	0.132	0.541	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MRPL45P2 tumor-vs-normal RNA expression · all MRPL45P2 data types