MRPL45P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRPL45P2 mutation is significantly associated with the RNA expression of many other genes, with 511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL45P2-associated genes across cancer lineages are KHDC1P1, RN7SL508P, and NIFKP2. Each is linked with MRPL45P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL45P2-to-partner and partner-to-MRPL45P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL45P2→partner) and Y-score (partner→MRPL45P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMKHDC1P1 →+0.120+5.097.004.00832
UCECRN7SL508P →+0.219+2.408.005.00932
SKCMNIFKP2 →+0.054+5.037<.001.00931
SKCMLINC02358 →+0.098+6.080<.001.00231
SKCMMRGPRX11P →+0.299+5.362<.001.00531
STADRNU1-35P →+1.212+4.401<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 511 associations by consensus.

Exploration