Across TCGA patient cohorts, MRPL45P2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL45P2-associated genes across cancer lineages are eIF4G, Annexin_VII, and Cyclin-E2. Each is linked with MRPL45P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL45P2-to-partner and partner-to-MRPL45P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL45P2→partner) and Y-score (partner→MRPL45P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.428	+3.169	.012	.020	3	1
UCEC	Annexin_VII →	-0.189	-3.169	.013	.020	3	1
UCEC	Cyclin-E2 →	+0.243	+3.009	.008	.019	3	1
UCEC	Tuberin →	+0.368	+2.817	.012	.036	2	1
UCEC	4E-BP1 →	+0.361	+2.837	.015	.035	2	1
UCEC	Notch1 →	+0.265	+3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

MRPL45P2 survival (RNA) · tumor vs normal (RNA) · all MRPL45P2 data types