MRPL45P1

Across TCGA pan-cancer cohorts, MRPL45P1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MRPL45P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MRPL45P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL45P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

KIRC, KICH, and ACC are the cancer types where MRPL45P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.440	0.657	<.001	132	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
ACC	DFS	Tertile	All	0.208	0.630	.001	48	view →
SKCM	OS	Median	All	0.831	0.742	.001	44	view →
UCEC	DFS	Quartile	All	0.762	0.869	.001	36	view →
HNSC	OS	Tertile	All	0.589	0.723	.006	30	view →
CHOL	DFS	Tertile	All	0.101	0.456	.010	27	view →
READ	OS	Tertile	IV	0.386	0.741	.037	18	view →
LGG	DFS	Tertile	All	0.613	0.752	.012	15	view →
OV	OS	Tertile	All	0.784	0.882	.014	14	view →
LUAD	DFS	Median	II,III,IV	0.815	0.650	.015	13	view →
GBM	DFS	Quartile	All	0.163	0.293	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MRPL45P1–KIRC (OS)

Open the KIRC breakdown →