MRPL45

Across TCGA patient cohorts, MRPL45 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL45-associated proteins across cancer lineages are LIG3, NSRP1, and ZNF830. Each is linked with MRPL45 in more than 8 cancer types. Because this analysis shows association rather than direction, both MRPL45-to-partner and partner-to-MRPL45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL45 versus LIG3 in LSCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL45→partner) and Y-score (partner→MRPL45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIG3 →	+0.646	+0.882	<.001	<.001	3	9
BRCA	NSRP1 →	+0.325	+0.586	<.001	<.001	3	8
LSCC	ZNF830 →	+0.358	+0.750	<.001	<.001	3	7
LSCC	SUPT6H →	+0.342	+0.803	<.001	<.001	3	7
BRCA	TAF15 →	+0.454	+0.629	<.001	<.001	3	7
LSCC	DHX8 →	+0.396	+0.806	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,991 associations by consensus.

MRPL45 vs LIG3 — LSCC

Explore this scatter interactively →