MRPL44

Across TCGA cell cohorts, MRPL44 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,204 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MRPL44-associated GO terms across cancer lineages are Mitochondrial translational elongation, Mitochondrial ribosome assembly, and Mitochondrial tRNA processing. Each is linked with MRPL44 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL44-to-partner and partner-to-MRPL44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translational elongation grouped by MRPL44-low versus MRPL44-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL44→partner) and Y-score (partner→MRPL44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Mitochondrial translational elongation →	+0.130	+0.500	<.001	<.001	3	14
BONE	Mitochondrial ribosome assembly →	+0.085	+0.547	.004	.003	3	13
BONE	Mitochondrial tRNA processing →	+0.168	+0.636	<.001	<.001	3	12
PANCREAS	Protein insertion into mitochondrial inner membrane from matrix →	+0.086	+0.457	.007	.002	2	13
CNS	Positive regulation of mitochondrial translation →	+0.088	+0.553	<.001	<.001	3	11
BONE	Mitochondrial RNA processing →	+0.113	+0.522	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,204 associations by consensus.

Mitochondrial translational elongation by MRPL44 expression — CNS

Explore this box plot interactively →