MRPL44

Across TCGA cell cohorts, MRPL44 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MRPL44-associated genes across cancer lineages are GLP1R, SPACA1, and ASB17. Each is linked with MRPL44 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL44-to-partner and partner-to-MRPL44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLP1R grouped by MRPL44-low versus MRPL44-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL44→partner) and Y-score (partner→MRPL44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GLP1R →	+0.141	+3.799	<.001	.003	3	1
OVARY	SPACA1 →	+0.011	+3.807	<.001	.009	3	1
OVARY	ASB17 →	+0.011	+3.807	<.001	.009	3	1
OVARY	CCDC60 →	+0.043	+3.643	.001	.002	3	1
OVARY	SCGB1D4 →	+0.065	+3.807	<.001	.009	3	1
OVARY	SALL3 →	+0.080	+3.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

GLP1R by MRPL44 expression — OVARY

Explore this box plot interactively →