MRPL43

Across TCGA patient cohorts, MRPL43 protein abundance is significantly associated with the RNA expression of many other genes, with 16,616 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL43-associated genes across cancer lineages are MT-CO2, ZEB2, and SCN1B. Each is linked with MRPL43 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPL43-to-partner and partner-to-MRPL43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL43 versus MT-CO2 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL43→partner) and Y-score (partner→MRPL43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT-CO2 →	+1.020	+0.240	<.001	<.001	3	8
BRCA	ZEB2 →	-0.864	-0.363	<.001	<.001	3	7
BRCA	SCN1B →	-0.618	-0.306	<.001	<.001	3	6
BRCA	CD33 →	-0.458	-0.268	<.001	<.001	3	6
HNSC	TNFSF8 →	-0.664	-0.199	<.001	<.001	3	6
COAD	FYN →	-0.909	-0.312	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,616 associations by consensus.

MRPL43 vs MT-CO2 — HNSC

Explore this scatter interactively →