MRPL42P4

Across TCGA pan-cancer cohorts, MRPL42P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MRPL42P4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPL42P4 RNA is repressed in tumor relative to normal tissue. In most cancer types MRPL42P4 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC, STAD, and HNSC are the cancer types where MRPL42P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL42P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.031	.011	4	view →
STAD	All	All	+0.036	.023	3	view →
HNSC	All	All	+0.015	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MRPL42P4–KIRC

Open the KIRC breakdown →