Across TCGA pan-cancer cohorts, MRPL42P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MRPL42P2’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where MRPL42P2 RNA is repressed in tumor relative to normal tissue. In most cancer types MRPL42P2 is over-expressed in tumor, although a few such as READ and LUSC show the opposite, repressed pattern.

READ, LUSC, and KICH are the cancer types where MRPL42P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL42P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	III,IV	−0.195	.030	2	view →
LUSC	Male	III,IV	−0.180	.048	1	view →
KICH	All	All	−0.033	.042	1	view →
KIRC	All	All	−0.033	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MRPL42P2 RNA expression & survival · all MRPL42P2 data types