MRPL4

Across TCGA patient cohorts, MRPL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,172 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL4-associated proteins across cancer lineages are DNMT1, RAVER1, and CDC37. Each is linked with MRPL4 in more than 8 cancer types. Because this analysis shows association rather than direction, both MRPL4-to-partner and partner-to-MRPL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL4 versus DNMT1 in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL4→partner) and Y-score (partner→MRPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNMT1 →	+0.534	+0.705	<.001	<.001	3	9
OV	RAVER1 →	+0.321	+0.671	<.001	<.001	3	7
OV	CDC37 →	+0.443	+0.785	<.001	<.001	3	7
LSCC	CHAF1B →	+0.500	+0.545	<.001	<.001	3	7
BRCA	DNMT1_S714 →	+0.739	+0.773	<.001	.001	3	7
OV	KRI1 →	+0.623	+0.640	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,172 associations by consensus.

MRPL4 vs DNMT1 — BRCA

Explore this scatter interactively →