MRPL4

Across TCGA cell cohorts, MRPL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,732 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL4-associated GO terms across cancer lineages are Mitochondrial ribosome assembly, rRNA metabolic process, and rRNA processing. Each is linked with MRPL4 in more than 16 cancer types. Because this analysis shows association rather than direction, both MRPL4-to-partner and partner-to-MRPL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial ribosome assembly grouped by MRPL4-low versus MRPL4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL4→partner) and Y-score (partner→MRPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.105	+1.235	<.001	<.001	3	17
OESOPHAGUS	rRNA metabolic process →	+0.137	+1.013	<.001	.002	3	16
OESOPHAGUS	rRNA processing →	+0.140	+1.013	<.001	.002	3	16
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.114	+1.047	.001	<.001	3	15
BONE	Electron transport coupled proton transport →	+0.114	+1.047	.001	<.001	3	15
OESOPHAGUS	U4 snRNA 3'-end processing →	+0.183	+0.952	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,732 associations by consensus.

Mitochondrial ribosome assembly by MRPL4 expression — BLOOD_Lymphoma

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