Across TCGA patient cohorts, MRPL38 mutation is significantly associated with the RNA expression of many other genes, with 350 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL38-associated genes across cancer lineages are HSPE1P16, RN7SL447P, and RNU6-591P. Each is linked with MRPL38 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL38-to-partner and partner-to-MRPL38 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL38→partner) and Y-score (partner→MRPL38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	HSPE1P16 →	+0.093	+4.513	<.001	.009	3	2
SKCM	RN7SL447P →	+0.131	+4.970	<.001	.005	3	2
UCEC	RNU6-591P →	+0.172	+5.481	<.001	<.001	3	2
UCEC	LINC02190 →	+0.097	+3.449	.001	<.001	3	2
BRCA	LINC02219 →	+0.151	+4.782	<.001	.003	3	1
SKCM	USH2A-AS1 →	+0.201	+4.563	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 350 associations by consensus.

Exploration

MRPL38 survival (RNA) · tumor vs normal (RNA) · all MRPL38 data types