MRPL37P1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MRPL37P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MRPL37P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPL37P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL37P1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRC, STAD, and KICH are the cancer types where MRPL37P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL37P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll+0.064.0126view →
STADMaleAll+0.279.0044view →
KICHAllIII,IV−0.068.0044view →
HNSCAllAll+0.060.0104view →
BRCAAllIII,IV−0.094.0062view →
CHOLAllAll+0.036.0072view →
LUSCAllII,III,IV+0.090.0451view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MRPL37P1–KIRC

Tumor-vs-normal expression box plot for MRPL37P1 RNA in KIRC.

Open the KIRC breakdown →

Exploration