MRPL36

Across TCGA patient cohorts, MRPL36 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL36-associated genes across cancer lineages are aDC, Megakaryocytes, and CD8+ naive T-cells. Each is linked with MRPL36 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL36-to-partner and partner-to-MRPL36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by MRPL36-low versus MRPL36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL36→partner) and Y-score (partner→MRPL36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.085	+3.008	.022	.019	3	1
UCEC	Megakaryocytes →	-0.025	-2.279	.043	.036	3	1
UCEC	CD8+ naive T-cells →	+0.044	+2.364	.001	.019	2	1
UCEC	Class-switched memory B-cells →	-0.057	-2.321	.045	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

aDC by MRPL36 expression — UCEC

Explore this box plot interactively →