MRPL35P4

Across TCGA pan-cancer cohorts, MRPL35P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MRPL35P4’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MRPL35P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL35P4 is over-expressed in tumor.

HNSC, UCEC, and LUAD are the cancer types where MRPL35P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL35P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.031	.012	4	view →
UCEC	All	IV	+0.339	.013	2	view →
LUAD	Female	All	+0.097	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MRPL35P4–HNSC

Open the HNSC breakdown →