MRPL35

Across TCGA cell cohorts, MRPL35 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,345 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPL35-associated GO terms across cancer lineages are Protein localization to condensed chromosome, tRNA C3-cytosine methylation, and Mitochondrial translation. Each is linked with MRPL35 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL35-to-partner and partner-to-MRPL35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by MRPL35-low versus MRPL35-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL35→partner) and Y-score (partner→MRPL35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.213	+1.023	.001	<.001	3	14
OVARY	tRNA C3-cytosine methylation →	+0.140	+0.573	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translation →	+0.113	+1.165	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cell junction assembly →	-0.062	-0.879	.001	.002	3	12
OESOPHAGUS	Protein localization to kinetochore →	+0.197	+0.956	.002	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Formation of translation preinitiation complex →	+0.087	+0.782	.007	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,345 associations by consensus.

Protein localization to condensed chromosome by MRPL35 expression — OESOPHAGUS

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