MRPL30P1

Across TCGA pan-cancer cohorts, MRPL30P1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MRPL30P1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MRPL30P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL30P1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

UCEC, HNSC, and LUSC are the cancer types where MRPL30P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL30P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	II,III,IV	+0.277	.011	6	view →
HNSC	All	II,III,IV	+0.114	.019	5	view →
LUSC	All	All	+0.111	.001	5	view →
COAD	All	II,III,IV	+0.174	.003	4	view →
KICH	All	All	−0.124	.004	3	view →
LUAD	All	IV	+0.480	.006	2	view →
LIHC	All	III,IV	+0.077	.030	2	view →
BLCA	Female	III,IV	+0.228	.020	1	view →
STAD	Male	II,III,IV	+0.138	.030	1	view →
THCA	All	All	−0.071	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MRPL30P1–UCEC

Open the UCEC breakdown →