MRPL3

Across TCGA patient cohorts, MRPL3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,587 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL3-associated genes across cancer lineages are ADAMTS10, FYN, and S1PR1. Each is linked with MRPL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPL3-to-partner and partner-to-MRPL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL3 versus ADAMTS10 in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL3→partner) and Y-score (partner→MRPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADAMTS10 →	-0.803	-0.274	<.001	<.001	3	8
UCEC	FYN →	-0.884	-0.331	<.001	<.001	3	7
BRCA	S1PR1 →	-0.784	-0.287	<.001	<.001	3	7
UCEC	MAGI2-AS3 →	-0.893	-0.327	<.001	<.001	3	7
BRCA	IFFO1 →	-0.707	-0.373	<.001	<.001	3	6
BRCA	PMP22 →	-0.726	-0.310	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,587 associations by consensus.

MRPL3 vs ADAMTS10 — UCEC

Explore this scatter interactively →