MRPL3

Across TCGA cell cohorts, MRPL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MRPL3-associated GO terms across cancer lineages are Pyrimidine nucleoside diphosphate biosynthetic process, tRNA wobble guanine modification, and Maturation of SSU-rRNA. Each is linked with MRPL3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRPL3-to-partner and partner-to-MRPL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine nucleoside diphosphate biosynthetic process grouped by MRPL3-low versus MRPL3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL3→partner) and Y-score (partner→MRPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Pyrimidine nucleoside diphosphate biosynthetic process →	+0.139	+0.555	<.001	<.001	3	16
LUNG_SCLC	tRNA wobble guanine modification →	+0.164	+0.700	.001	<.001	3	16
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.121	+0.713	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Ribosomal small subunit biogenesis →	+0.109	+0.938	<.001	<.001	3	15
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.116	+0.607	.008	.007	2	16
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.160	+0.896	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Pyrimidine nucleoside diphosphate biosynthetic process by MRPL3 expression — SOFT_TISSUE

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