MRPL28

Across TCGA cell cohorts, MRPL28 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,685 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRPL28-associated GO terms across cancer lineages are Pyrimidine deoxyribonucleoside triphosphate metabolic process, Regulation of cytokinetic process, and Double-strand break repair via break-induced replication. Each is linked with MRPL28 in more than 11 cancer types. Because this analysis shows association rather than direction, both MRPL28-to-partner and partner-to-MRPL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine deoxyribonucleoside triphosphate metabolic process grouped by MRPL28-low versus MRPL28-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL28→partner) and Y-score (partner→MRPL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Pyrimidine deoxyribonucleoside triphosphate metabolic process →	+0.123	+0.831	<.001	<.001	3	12
URINARY_TRACT	Regulation of cytokinetic process →	+0.101	+0.774	.001	<.001	3	10
BONE	Double-strand break repair via break-induced replication →	+0.276	+0.615	.001	.001	3	10
URINARY_TRACT	Regulation of mitotic cytokinetic process →	+0.101	+0.774	.001	<.001	3	10
URINARY_TRACT	Positive regulation of mitotic cytokinetic process →	+0.101	+0.774	.001	<.001	3	10
BONE	Termination of RNA polymerase III transcription →	+0.162	+0.630	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,685 associations by consensus.

Pyrimidine deoxyribonucleoside triphosphate metabolic process by MRPL28 expression — OVARY

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