MRPL24

Across TCGA pan-cancer cohorts, MRPL24 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of MRPL24’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPL24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL24 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where MRPL24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+0.833	<.001	12	view →
COAD	Female	II,III,IV	+0.622	<.001	10	view →
KIRP	All	II,III,IV	+0.548	<.001	10	view →
HNSC	Male	II,III,IV	+0.532	<.001	10	view →
LIHC	Male	All	+1.692	<.001	9	view →
LUAD	Female	III,IV	+1.205	<.001	9	view →
LUSC	Female	All	+1.005	<.001	7	view →
KICH	Female	II,III,IV	−1.525	<.001	6	view →
BRCA	All	III,IV	+0.944	<.001	6	view →
BLCA	Female	III,IV	+0.845	.001	6	view →
STAD	All	All	+0.535	.001	5	view →
PAAD	Male	All	+0.155	.009	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

MRPL24–KIRC

Open the KIRC breakdown →